Tell us a little bit about yourself!
Hi! I’m Dr. Elizabeth Chappell; I’m a senior consultant in analytical services at BioTechLogic, Inc. I earned my PhD in Pharmaceutical Sciences from UNC Chapel Hill in 2013. Prior to my postdoctoral advisor introducing me to the JGP Fellowship, I had never heard of the program or Dr. Pool. But I applied and, in 2014, I was honored to receive the JGP Fellowship. At the time, I was a postdoctoral research associate mentoring under Dr. Dougald Monroe at UNC-Chapel Hill.
What did your research project focus on?
The project was titled “In vivo Imaging of Bleeds in Hemophilia B.” During this research, I developed a model for characterizing bleeding in hemophilia, particularly in joints. Using mouse models of hematoma formation and knee joint bleeding, I used 3D fluorescent imaging technology in "living" hemophilia B mice to better trace bleeding over time- from induction of a bleed to its resolution. This project provided additional insights on the basic science underlying hemophilic bleeds, as well as the optimal interventions and timing of treatment to potentially prevent damage caused by bleeds.
How did the JGP Fellowship support your research at the time? Does it continue to influence your work now?
The fellowship provided stipend support and research funds when I was doing postdoctoral research in hematology. The method development and protein therapeutic skills I learned during that time have helped me in my analytical career.
The Judith Graham Pool Postdoctoral Research Fellowship has been supporting basic science and pre-clinical research to expand our understanding of bleeding disorders since 1972. Learn more here.
