NBDF funds a broad range of research programs that seek to increase our understanding of the science behind bleeding disorders, how they affect people's lives, and pathways to better treatments and cures.

Transposon Mediated Gene Therapy of Hemophilia

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Li Liu

Identification of Chemical Modifiers of Coagulation

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
David Buchner

Proficient AAV Vectors for the Treatment of Hemophilia B (2005)

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Gene Therapy
Author(s):
Michael Herbert

Mechanism for the Ectopic Expression of Galgt2 in Endothelial Cells

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Author(s):
Jill Marie Johnson
Christine_Kempton

Platelet Mechanism Regulating Thrombin Generation

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Christine L. Kempton

Per Dr. Kempton, the JGP assisted her in determining the direction of her future research. As a result of her JGP project, Dr. Kempton was published in ATVB and published several abstracts.

Purification and Characterization of Vitamin K Epoxide Reductase

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Vitamin K
Author(s):
Tao Li

Development of Self-Complimentary (SC) Adeno-Associated Virus Type 5 (AAV-5) Vectors for Gene Therapy of Hemophilia B

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia B (Factor IX/F9)
Author(s):
Zhijian Wu

Structure of Factor VIII’s C Domains and their Epitopes

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Author(s):
Ting-Chang Hsu

Identification of Complement-Type Repeats of LRP Responsible for Interaction with A2 Domain of Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Author(s):
Andrey Garunovich Sarafanov

Exploiting Mouse Models to Elucidate the Cellular and Molecular Mechanisms Involved in the Pathogenesis of Platelet Storage Pool Deficiencies

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Lisa S. Webb

Function of Coagulation Factor V in Plasma and Platelet Pools

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Hongmin Sun

Development of a Novel Genomic Transfer Approach for the Treatment of Hemophilia Based on Transduction of Adipose Tissue Using Replication-Defective HSV-1 Vectors

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Julie Fradette
Anja_Ehrhardt

Development of Improved Adenoviral Vectors Lacking All Adenoviral Coding Sequences for Hemophilia Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Anja Ehrardt

Molecular Mechanisms of Combined Factors V and VIII Deficiency

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Factor V
Hemophilia A (Factor VIII/F8)
Author(s):
Bin Zhang

Study of Interactive Sites of Factor VIIIa with Factor IXa

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Peter Vincent Jenkins

Retroviral Vector-Mediated Gene Therapy for Canine Hemophilia B

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia B (Factor IX/F9)
Author(s):
Lingfei Xu

Treatment of a Mouse Model of Hemophilia Using AAV Vectors Expressing Murine Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Gene Therapy
Author(s):
Cathryn Sanghae Mah

Correction of Factor VIII Deficiency by Nonprimate Lentivirus-Based Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Author(s):
Yubin Kang

Induction of Immune Tolerance to Factor IX

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Inhibitors
Author(s):
Bing-guan Chen

Vascular Bed-Specific Regulation of the VWF Gene

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Author(s):
Jo Chao Tsai