NBDF funds a broad range of research programs that seek to increase our understanding of the science behind bleeding disorders, how they affect people's lives, and pathways to better treatments and cures.

Roland Herzog

Immunology of Liver-Derived Expression of Factor IX from AAV Vectors

Year:
-
Grants:
Career Development Award
Hemophilia B (Factor IX/F9)
Gene Therapy
Author(s):
Roland W. Herzog

Correction of Hemophilia with Lentiviral Vectors

Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Gene Therapy
Author(s):
Tal Kafri
Steven Pipe

Development and Characterization of Novel Genetically Engineered Factor VIII Molecules with Increased Activity and Stability

Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Author(s):
Steven Wesley Pipe

Treatment of a Mouse Model of Hemophilia Using AAV Vectors Expressing Murine Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Gene Therapy
Author(s):
Cathryn Sanghae Mah

Induction of Immune Tolerance to Factor IX

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Inhibitors
Author(s):
Bing-guan Chen

Vascular Bed-Specific Regulation of the VWF Gene

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Author(s):
Jo Chao Tsai

New Therapeutics for Hepatitis C

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hepatitis/Liver Disease
Author(s):
You-Kyung Hwang

Mechanisms Involved in Transduction of Human Lentivirus in Liver: A Strategy for Hemophilia Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Frank Park
Mark_Reding

T Cell Epitopes on Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
HIV/AIDS
Author(s):
Mark Thomas Reding
Paul_Monahan

AAV Hemophilia Gene Therapy Vectors

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Paul E. Monahan

Impact of VWF on Factor VIII Gene Targeting

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Hemophilia A (Factor VIII/F8)
Author(s):
Jonathan Bernard Rosenberg

Vitamin K-Dependent Carboxylase (1997)

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Vitamin K
Author(s):
Beth A. Bouchard

Factor VIII Delivery via Skin

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Author(s):
Steven Shahin Fakharzadeh

Vitamin K-Dependent Carboxylase (1996)

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Vitamin K
Author(s):
Dewey G. McCafferty

Interaction of Factor VIII with Factor IXa

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Degang Zhong

Persistent Expression of Factor IX

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Author(s):
David Bruce Schowalter

Gene Therapy for Hemophilia B

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia B (Factor IX/F9)
Author(s):
Qicheng Yang
Scott_Tenenbaum

HIV Resistance in Hemophiliacs

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
HIV/AIDS
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Scott A. Tenenbaum

Per Dr. Tenenbaum, the JGP provided him with the necessary framework to complete his Postdoctoral Fellowship at Duke University Medical Center and his first academic position at SUNY, where he is currently a Professor specializing in RNA Nanotechnology and Genomics. Although he has not remained in the field of hematology, his current research does intersect with many diseases, including those in the field of hematology (and specifically, hemophilia). The intersection is in relation to gene therapy technology that he is developing.

Dwight_Koeberl

Factor VIII Gene Therapy Vectors

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Author(s):
Dwight D. Koeberl

Factor VIII–Specific T Lymphocytes

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
HIV/AIDS
Author(s):
Sylvia T. Singer
Per Dr. Singer, the JGP greatly influenced her career in research. It allowed her to focus on a research project, understand the process of asking a question/creating a hypothesis and developing (with guidance) a research plan; as well as analyze the date, present it (at NHG meeting at ASH) and write/publish it. It sparked her interest in hematology and in clinical research. She has pursued her work in the field of Pediatric Hematology and has obtained funding for research (including a K23 award). She has continued with ‘benign hematology’, focusing on Thalassemia (clinical and clinical research), as well as general hematology and hemostasis. Recently, she has become more involved in hemostasis (clinical care and sponsored studies related to bleeding/thrombosis).