Research Presented at Our Conference | National Bleeding Disorders Foundation

Efficacy and safety of pdFX, a new high-purity factor X concentrate, in patients with mild to severe hereditary factor X deficiency undergoing surgery

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

New Products

RESEARCHERS:

Miguel Escobar, Günter Auerswald, Austin Steven, Huang James N, Miranda Norton, Carolyn Millar

Increase or Maintenance of Physical Activity in Patients Treated with Recombinant Factor IX Fc Fusion Protein (rFIXFc) in the B-LONG and Kids B-LONG Studies

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research/Clinical Trials

RESEARCHERS:

Amy Shapiro, Roshni Kulkarni, Jerzy Windyga, Margaret Ragni, John Pasi, Margareth Ozelo, Elisa Tsao, Geoffrey Allen, Baisong Mei

Target Joint Spontaneous annualized bleed rate (sABR) Reduction: results from a pivotal trial of once weekly BeneFIX (nonacog alfa) in Hemophilia B subjects

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Bartholomew Tortella, Marcus Carr, Pablo Rendo, Lynne Smith, Kaan Kavakli

Relative Health Status of Young Adults in the Hemophilia Utilization Group Studies (HUGS)

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Quality of Life/Outcomes Research

RESEARCHERS:

Randall Curtis, Brenda Riske, Judith Baker, Megan Ullman, Xiaoli Niu, Kristi Norton, Marion Koerper, Mimi Lou, Michael Nichol

An Evaluation of the Switch from Standard Factor VIII Prophylaxis to Prophylaxis with an Extended Half-Life, Pegylated, Full-length Recombinant Factor VIII (BAX 855)

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research/Clinical Trials

RESEARCHERS:

Oleksandra Stasyshyn, Ralph Gruppo, Barbara Konkle, Tung Wynn, Marilyn Manco-Johnson, Pratima Chowdary, Vladimir Komrska, Laimonas Griskevicius, Elaine Eyster, Krzysztof Chojnowski, Werner Engl, Lisa Patrone, Brigitt Abbuehl

Reduced Polyethylene Glycol–Conjugated B-Domain–Deleted Factor VIII (PEG-BDD-FVIII) Clearance: Selective PEG Steric Modulation Without Affecting Potency

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Eric Blasko, Lilley Leong, Derek Sim, Liang Tang, Jim Wu, Katalin Kauser, Babu Subramanyam

Effect of hemophilia treatment center monitoring on bleeding rates

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Quality of Life/Outcomes Research

RESEARCHERS:

Marc Lara, Natalie Duncan, Raquel Andres, John Chapin, Catherine McGuinn

The Effects of Hemophilia on Socialization

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Psychosocial Issues

RESEARCHERS:

Aric Parnes, Christine Mitchell, Rachel Wentz, Federico Campigotto, Latoya Lashley, Cathee Brunswick, Donna Neuberg, Judith Lin

Intervention of Mexicans children and teenagers with hemophilia for their social integration

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Psychosocial Issues

RESEARCHERS:

Ana Paola Abreu Bastar, Ana Laura Abreu Bastar

Quantitative research into people with hemophilia and caregiver perceptions of pre-filled solvent syringe (MixPro®)

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

New Products

RESEARCHERS:

Kate Khair, Jim Munn, Andrew Scott, Robyn Shoemark, Julia Spires, Akin Akinwonmi

Personalization of Treatment Regimens for Physically Active Patients: A Comparison of Factor VIII and Extended Half-life Treatment Regimens

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

New Products

RESEARCHERS:

Elizabeth L Schwartz, Yan Xiong, Josh Epstein, Bruce Ewenstein, Leonard A. Valentino

Pharmacist/Provider Collaboration needed to Optimize Dosing Regimens in Order to Reduce Bleed Rates in Hemophilia A Patients on Prophylaxis Regimens

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Collaboration/Team Models

RESEARCHERS:

Joan Couden BSN, RN, Tina Dooley Pharm. D., Kim Milenski RPH

Cost of Treating Thrombotic Events in a US Population of Von Willebrand Disease Patients

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Alexandra Khachatryan, Yan Xiong

Interim results of the B-YOND study evaluating long-term safety and efficacy of recombinant factor IX Fc (rFIXFc) in children with severe hemophilia B

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research/Clinical Trials

RESEARCHERS:

Carolyn Bennett, Beatrice Nolan, Roshni Kulkarni, Kathelijn Fischer, David Perry, Christopher Barnes, Huixing Yuan, Alejandra Ramirez-Santiago, Glenn F Pierce, Baisong Mei

The impact of missing one or two infusions per month: a comparison of rFVIII and rFVIIIFc regimens

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Quality of Life/Outcomes Research

RESEARCHERS:

Josh Epstein, Elizabeth L. Schwartz, Yan Xiong, Morgan Bron, Jason Booth, Armin Reininger, Alessandro Gringeri

SPINART 3-Year Analyses: Patient- and Joint-Level Changes in Colorado Adult Joint Assessment Scale and Magnetic Resonance Imaging Scores With Bayer’s Sucrose-Formulated Recombinant Factor VIII (rFVIII-FS) in Adolescents and Adults

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research/Clinical Trials

RESEARCHERS:

Sharon Funk, Björn Lundin, Walter Hong

Leading an Active Lifestyle with Hemophilia B: Estimating the Bleeding Risk with Different FIX Treatment Regimens

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Yan Xiong, Alexandra Khachatryan, Josh Epstein

A Half-Life Extended Fusion Peptide Inhibitor of TFPI Improves Hemostasis in Preclinical Models of Hemophilia

AWARDED/PRESENTED: 2015

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Michael Dockal, Rudolf Hartmann, Thomas Polakowski, Erwin Panholzer, Willibald Kammlander, Frank Osterkamp, Ulrich Reineke, Alexandra Schiviz, Werner Hoellriegl, Friedrich Scheiflinger