Research Presented at Our Conference

The expression of codon-optimized blood coagulation factor VIII using a lentiviral system

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Svetlana Shestopal, John McVey, Timothy Lee, Andrey Sarafanov

Hemophilia Inhibitor PUP Study (HIPS)

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Available Clinical Studies

RESEARCHERS:

Deborah Brown, Elena Santagostino, Christoph Hofbauer

The use of combination therapy with plasma derived and recombinant factor VIII in patients with hemophilia A: a single institution experience

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Betsy Koval, Chrissy Kennedy, Amy Dunn, Shannon Meeks

Point-of-care musculoskeletal ultrasound is critical for the diagnosis of hemarthroses and soft tissue inflammation in adult patients with painful hemophilic arthropathy

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Orthopedic and Physical Therapy

RESEARCHERS:

Wesley Kidder, Sonha Nguyen, John Larios, Jaclyn Bergstrom, Arnold Ceponis, Annette von Drygalski

Pain and Arthropathy Impact Quality of Life of Young Adults With Hemophilia (ages 18-30) in the United States: Observations From the Hemophilia Experiences, Results and Opportunities (HERO) Study

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Psychosocial Issues

RESEARCHERS:

Angela Forsyth, Sarah Hawk, Michelle Witkop, Angela Lambing, Chris Guelcher, Randall Curtis, Neil Frick, Laureen Kelley, Michelle Rice, David Cooper

The effects of FXIa on clot formation and lysis in the thrombin generation assay

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

William Chang, Kevin Xin, Timothy Lee, Mikhail Ovanesov

Addressing patient concerns about product switching in hemophilia A: Evaluating turoctocog alfa data from the guardian™ clinical trial program

AWARDED/PRESENTED: 2014

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Roshni Kulkarni, Irina Matytsina

Determining the impact of instrument variation and automated software algorithms on the thrombin generation test under hemophilia treatment conditions

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Samuel A Woodle, Timothy K Lee, Mikhail V Ovanesov

B-LONG: Phase 3 Study of Long-Lasting Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Hemophilia B

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Jerry Powell, Margaret Ragni, Leonard Valentino, Neil Josephson, Marilyn Manco-Johnson, Geoffrey Allen, Haiyan Jiang, Jurg Sommer, Jennifer Dumont, Aoife Brennan, Alvin Luk, Glenn Pierce

Better Adherence to Prescribed Treatment Regimen is Associated with Less Chronic Pain among Adolescent and Young Adults with Moderate or Severe Hemophilia

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Michelle Witkop, John McLaughlin, Angela Lambing, James Munn, Terry Anderson, Bartholomew Tortella

Burden of Bleeding Episodes Among Persons With Hemophilia B

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Peer Support/Outreach/Integration Models

RESEARCHERS:

Xiaoli Niu, Jiat-Ling Poon, Judith Baker, Megan Ullman, Mimi Lou, Marion Koerper, Kathy Parish, Randall Curtis, Mike B. Nichol

Efficacy and safety of a novel rFIX (BAX326): phase III study in previously treated patients with severe or moderately severe hemophilia B undergoing surgical or other invasive procedures

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Jerzy Windyga, Toshko Lissitchkov, Oleksandra Stasyshyn, Vasily Mamonov, Helieh Ghandehari, Miranda Chapman, Sandor Fritsch, Borislava G. Pavlova, Wing-Yen Wong, Brigitt E. Abbuehl

Cardiovascular management in hemophilia: acute coronary syndromes – an assessment by the ADVANCE Working group on applicability of the ESC Guidelines

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Gerard Dolan, Peter Staritz, Philippe de Moerloose, Roger Schutgens

Overview of a global clinical trial program with turoctocog alfa, a new recombinant factor VIII: the guardian™ program

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Pawel Laguna, Vladimir Vdovin, Lina Rageliene, Lydia Abad-Franch, Anders Lindblom

Outcomes of Total Knee and Hip Arthroplasty for Hemophilic Arthropathy

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Orthopedic and Physical Therapy

RESEARCHERS:

Yuika Goto, Britt Holderness, Laurel McKernan, Philip Bernini, Deborah Ornstein

Characterization of the Binding of a Novel Recombinant Single-Chain FVIII to von Willebrand Factor

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Biomedical/Coagulation Research

RESEARCHERS:

Philipp Claar, Joachim Röder, Sabine Zollner, Thomas Weimer, Gerhard Dickneite, Stefan Schulte

FEIBA PROOF: A Prospective, open-label, randomized, parallel study with FEIBA NF to evaluate the efficacy and safety of prophylactic versus on-demand treatment in haemophilia A or B subjects with inhibitors

AWARDED/PRESENTED: 2013

GRANT/PROGRAM:

Bleeding Disorders Conference

Clinical Research

RESEARCHERS:

Sandra V. Antunes, Srilatha Tangada, Oleksandra Stasyshyn, Vasily Mamonov, Julia Phillips, Norma Guzman-Becerra, Jennifer Doralt, Bruce Ewenstein, Wing Yen Wong